ISSN 0371-0874, CN 31-1352/Q

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噪声暴露所致的应激反应及其测量方法

范紫慧, 邹建文, 陈其才, 付子英*

华中师范大学生命科学学院,遗传调控与整合生物学湖北省重点实验室,武汉 430079

摘要

噪声作为现代生活中不可避免的一种应激(压力)源,对动物的行为和生理等多方面均有影响。行为上的改变可能是由于动物体内激素分泌的变化所驱动。当面临噪声应激时,动物体内以下丘脑-垂体-肾上腺(hypothalamic-pituitary-adrenal, HPA)轴为主的神经内分泌系统被激活,促进动物分泌释放应激激素,进而产生一系列行为变化。动物行为上的改变可以被直接观察到,但激素水平等生理学指标变化则需要借助一定的方法才能准确地测量。目前,已有许多相关研究测量了不同噪声条件下动物应激激素水平的变化。本文以糖皮质激素为例,总结了应激激素的不同测量方法,尤其是非侵入性测量方式,并比较了不同方法的优点和不足之处,可为相关问题的研究提供多种测量方式的选择,也能够进一步了解动物压力来源,以给动物提供更好的栖息环境。

关键词: 噪声; 应激反应; 糖皮质激素; 非侵入性测量

Noise exposure-induced stress response and its measurement methods

FAN Zi-Hui, ZOU Jian-Wen, CHEN Qi-Cai, FU Zi-Ying*

School of Life Sciences and Hubei Key Laboratory of Genetic Regulation and Integrative Biology, Central China Normal University, Wuhan 430079, China

Abstract

Noise, as an unavoidable stress (pressure) source in the modern life, affects animals in many ways, both behaviorally and physiologically. Behavioral changes may be driven by changes in hormone secretion in animals. When animals face with noise stress, the neuroendocrine systems, mainly the hypothalamic-pituitary-adrenal (HPA) axis, are activated, which promotes the secretion and release of stress hormones, and then leads to a series of behavioral changes. The behavioral changes can be easily observed, but the changes in physiological indicators such as hormone levels need to be accurately measured. Currently, many studies have measured the variations of stress hormone levels in animals under different noise conditions. Taking glucocorticoid as an example, this paper summarizes the different measurement methods of stress hormones, especially the non-invasive measurement methods, and compares the advantages and shortcomings of them. It provides a variety of measurement choices for the study of related issues, and also helps us to further understand the sources of animal stress, in order to provide a better habitat for animals.

Key words: noise; stress response; glucocorticoid; non-invasive measurement

收稿日期:  录用日期:

通讯作者:付子英  E-mail:

DOI: 10.13294/j.aps.2024.0036

引用本文:

范紫慧, 邹建文, 陈其才, 付子英. 噪声暴露所致的应激反应及其测量方法[J]. 生理学报 2024; 76 (3): 407-417.

FAN Zi-Hui, ZOU Jian-Wen, CHEN Qi-Cai, FU Zi-Ying. Noise exposure-induced stress response and its measurement methods. Acta Physiol Sin 2024; 76 (3): 407-417 (in Chinese with English abstract).