ISSN 0371-0874, CN 31-1352/Q



张宇1, 韩中胜1,2,*

1山西医科大学生理学系,太原 030001;2 美国西雅图儿童研究所综合脑科学研究中心,西雅图 98101



关键词: 孤独症谱系障碍; 孤独偏才; 获得性偏才; 神经生物学原理


Neurobiological mechanisms of autistic savant and acquired savant

Zhang Yu1, Victor Z Han1,2,*

1Department of Physiology, Shanxi Medical University, Taiyuan 030001, China;2Center for Integrative Brain Research, Seattle Children’s Research Institute, Seattle, WA 98101, USA


The autism spectrum is a pervasive developmental disorder characterized by profound social and verbal communication deficits, stereotypical motor behaviors, restricted interests, and cognitive abnormalities. It affects approximately 1% of children in most of the reported nations and regions. One of the most fascinating and mysterious features of autism, however, is the remarkable talent
frequently found in people affected by it, namely autistic savant. A parallel and equally mysterious phenomenon is that some otherwise normal and ordinary individuals develop similarly remarkable talent after brain injuries, a disorder known as acquired savant. After
decades of intensive investigation, significant progress has been made in these fields. Current studies indicate that autistic savant and acquired savant are neuropathologically related, and these disorders share many neurobiological mechanisms. This review summarizes current knowledge of autism and both two savant types, and how it may aid our understanding of higher brain functionalities.

Key words: autistic spectrum disorder; autistic savant; acquired savant; neurobiological mechanisms

收稿日期:2017-08-28  录用日期:2017-12-08

通讯作者:韩中胜  E-mail:

DOI: 10.13294/j.aps.2017.0090


张宇, 韩中胜. 孤独症患者的偏才和获得性偏才现象及其神经生物学机理[J]. 生理学报 2018; 70 (2): 201-210.

Zhang Yu, Victor Z Han. Neurobiological mechanisms of autistic savant and acquired savant. Acta Physiol Sin 2018; 70 (2): 201-210 (in Chinese with English abstract).