ISSN 0371-0874, CN 31-1352/Q

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氯化钠对培养的大鼠主动脉平滑肌细胞的心房钠尿肽受体的调节

廖永伯, 张琪, 丁金凤

中国医学科学院心血管病研究所

摘要

高盐培育液孵育24h后, 大鼠主动脉平滑肌细胞表面心房钠尿肽(ANP)受体的 亲和力改变不明显, 但受体数量下调, 细胞对ANP引起的环磷酸鸟苷增加反应明 显降低。图4表3参22

关键词: 培养的大鼠主动脉平滑肌细胞; 心房钠尿肽(ANP); 受体; 细胞内 cGMP; 下行调节; 高盐

Regulation of atrial natriuretic peptide receptor in cultured aortic vascular smooth muscle cells from stroke-prone spontaneously hypertensive and Wistar-Kyoto rats

Liao Yongbo, Zhang Qi, Ding Jinfeng

Cardiovasc. Inst., Chin. Acad. Med. Sci.

Abstract

Key words: Cultured vascular smooth muscle cells (VSMC);Atrial natriuretic peptide (ANP);Receptor;Intracellural cGMP;Down-regulation;High NaCl

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引用本文:

廖永伯, 张琪, 丁金凤. 氯化钠对培养的大鼠主动脉平滑肌细胞的心房钠尿肽受体的调节[J]. 生理学报 1991; 43 (4): .

Liao Yongbo, Zhang Qi, Ding Jinfeng. Regulation of atrial natriuretic peptide receptor in cultured aortic vascular smooth muscle cells from stroke-prone spontaneously hypertensive and Wistar-Kyoto rats. Acta Physiol Sin 1991; 43 (4): (in Chinese with English abstract).