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气体信号分子在女性生殖系统中的作用

高路, 伍天文, 倪鑫^*

第二军医大学生理学教研室和教育部分子神经生物学教研室，上海 200433

摘要

生物体内合成的内源性气体分子：NO，CO以及H2S，具有多种生物学功能因而被称为气体信号分子。这三种气体信号分子在许多生理与病理过程中发挥重要作用，如调节血管紧张性、炎症反应、生殖功能等。本文主要对这三种气体信号分子在女性和雌性动物生殖系统中的分布和生物学功能进行综述。

关键词： 一氧化氮; 一氧化碳; 硫化氢; 生殖

分类号：R339.2;Q492

Gas transmitters in female reproductive system

GAO Lu, WU Tian-Wen, NI Xin^*

Department of Physiology and the Key Laboratory of Molecular Neurobiology of Ministry of Education, The Second Military Medical University, Shanghai 200433, China

Abstract

Nitric oxide, carbon monoxide and hydrogen sulfide synthesized endogenously in living organisms produce an array of disparate biological effects, so as to be considered as gas transmitters. These three gaseous molecules play important roles in many physiological and pathological processes in the bodies, such as the regulation of vascular tone and inflammatory responses as well as reproductive function. This review mainly focuses on the distribution and biological functions of these three gas transmitters in female reproductive tissues.

Key words: Nitric oxide; carbon monoxide; hydrogen sulfide; female

收稿日期：2016-01-28　　录用日期：2016-09-20

通讯作者：倪鑫　　E-mail: nixinsmmu@hotmail.com

引用本文：

高路, 伍天文, 倪鑫. 气体信号分子在女性生殖系统中的作用[J]. 生理学报 2016; 68 (5): 611-620.

GAO Lu, WU Tian-Wen, NI Xin. Gas transmitters in female reproductive system. Acta Physiol Sin 2016; 68 (5): 611-620 (in Chinese with English abstract).