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汉族与朝鲜族人群体循环血管阻力及相关因素的比较

潘阳杏, 齐保申, 周晓梅, 韩少梅, 朱广瑾^*

中国医学科学院基础医学研究所、北京协和医学院基础医学院生理与病理生理学系，北京 100005

摘要

本文比较了牡丹江、海林地区汉族与朝鲜族人群体循环血管阻力(systemic vascular resistance, SVR)差异及相关影响因素。采用BIOZ 无创血流动力学心功能监护仪，检查了1 647 名汉族和876 名朝鲜族人SVR、体循环血管阻力指数(systemicvascular resistance index, SVRI)、收缩压(systolic blood pressure, SBP)、舒张压(diastolic blood pressure, DBP)、平均动脉压(mean arterial pressure, MAP)、心输出量(cardiac output, CO)、心指数(cardiac output index, CI)和心率(heart rate, HR)。采用SPSS 15.0 软件统计分析所得数据。结果表明汉族人群男性和女性SVR/SVRI 分别低于同性别、同年龄组朝鲜族人群。t 检验比较两民族之间的差异，结果显示：(1) SVR 存在统计学差异的组别有：男性41~50、51~60、61~70 岁组(P<0.001)，31~40 岁组(P<0.01)，19~30 岁组(P<0.05)；女性 15~18、31~40、51~60 岁组(P<0.001)，41~50 岁组(P<0.01)，61~70 岁组(P<0.05)。(2) SVRI 存在统计学差异的组别有：男性41~50、51~60 岁组(P<0.05)；女性 10~14、51~60 岁组(P<0.001)，15~18、31~40 岁组(P<0.01)，41~50 岁组(P<0.05)。协方差分析表明，排除了性别、年龄、体重指数(body mass index,BMI)等因素的影响后，两民族之间SVR/SVRI 仍然存在统计学差异(P<0.001)。多元线性回归显示：对两民族之间SVR 差异影响的贡献大小依次为MAP、DBP、CI、SBP、HR；对SVRI 差异的影响强弱依次为MAP、DBP、SBP、CI、HR。以上结果表明，SVR/SVRI 的升高与朝鲜族血压高于汉族有关。

关键词： 血管阻力; 血压; 心输出量; 体重指数; 汉族人; 朝鲜族人

分类号：R331.3

[Comparison of the systemic vascular resistance and the correlative factors in Han and Korean populations of China.] [Ariticle in Chinese]

PAN Yang-Xing, QI Bao-Shen, ZHOU Xiao-Mei, HAN Shao-Mei, ZHU Guang-Jin*

Department of Physiology and Pathophysiology, Institute of Basic Medical Sciences

Abstract

In the present study, the differences in systemic vascular resistance (SVR) and the correlated risk factors between Han and Korean residents were investigated. 1 647 Hans and 876 Koreans from Mudanjiang and Hailin areas of Heilongjiang Province were examined with BIOZ Cardio Dynamics Monitor. A series of factors were determined, including SVR, systemic vascular resistance index (SVRI), systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), cardiac output (CO), cardiac output index (CI) and heart rate (HR). The data were analyzed with SPSS 15.0 statistic software. When SVR/SVRI were compared between Han and Korean populations by t-test, it was shown that statistic difference existed in the following age and gender groups: (1) For SVR: male 41-50, 51-60, and 61-70 (P<0.001), 31-40 (P<0.01), 19-30 (P<0.05) age groups; female 15-18, 31-40, 51-60 (P<0.001), 41-50 (P<0.01), and 61-70 (P<0.05) age groups; (2) For SVRI, male 41-50, 51-60 (P<0.05) age groups; female 10-14, 51-60 (P<0.001), 15-18, 31-40 (P<0.01), and 41-50 (P<0.05) age groups. Covariance analysis suggests that, excluding the contributions of gender, age and body mass index (BMI), the differences in SVR/SVRI between the two populations are still significant (P<0.001). Multiple linear regression analysis reveals that SVR difference between Han and Korean populations is attributed to MAP, DBP, CI, SBP, HR; While SVRI difference between two populations is attributed to MAP, DBP, SBP, CI, HR, strongly to weakly, respectively. These results suggest the higher SVR and SVRI are possibly correlated with the relatively higher blood pressure of Korean, compared with that of Han population.

Key words: vascular resistance; blood pressure; cardiac output; body mass index; Han population; Korean population

收稿日期：2009-04-07　　录用日期：2009-11-11

通讯作者：朱广瑾　　E-mail: zhugj@pumc.edu.cn

引用本文：

潘阳杏, 齐保申, 周晓梅, 韩少梅, 朱广瑾. 汉族与朝鲜族人群体循环血管阻力及相关因素的比较[J]. 生理学报 2009; 61 (6): 544-550.

PAN Yang-Xing, QI Bao-Shen, ZHOU Xiao-Mei, HAN Shao-Mei, ZHU Guang-Jin* . [Comparison of the systemic vascular resistance and the correlative factors in Han and Korean populations of China.] [Ariticle in Chinese] . Acta Physiol Sin 2009; 61 (6): 544-550 (in Chinese with English abstract).