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中枢神经元树突电活动和树突返传动作电位在突触可塑性调控中的作用-----悼念树突功能研究的先驱张香桐院士

乔健天, 韩中胜, 祁金顺

山西医科大学神经生物学研究室.山西,太原 030001；美国俄勒冈健康与科学大学神经科学研究所.波特兰 97006

摘要

该文回顾了张香桐院士在上世纪50年代完成的有关神经元树突电活动和功能特性的先驱性研究工作，简要介绍了此后成为神经科学研究热点之一的树突在中枢突触传递和突触可塑性形成中所起作用的研究概况，籍以说明张香桐院士不愧为神经科学研究历史上做出过突出贡献的人物之一。

关键词： 张香桐; 大脑皮层; 顶树突; 树突电位; 轴突始段; 树突返传动作电位; 神经元突触可塑性

Electrophysiological characteristics of central neuronal dendrites and roles of dendritic back--propagating action potentials in modifications of synaptic plasticity

Qiao Jiantian, Han Zhongsheng, Qi Jinshun

Laboratory of Neurobiology, Shanxi Medical University.Taiyuan 030001,Shanxi；USA

Abstract

For expressing the condolences on the passing away of Dr. Hsiang-Tung Chang, one of the distinguished members of the Chinese Academia of Sciences, the pioneer studies on cortical dendritic potentials that Dr. Chang carried out in the 1950s and the prosperous progresses since then, especially, concerning the modifications of synaptic plasticity by the dendritic back-propagating action potentials were briefly reviewed.

Key words: Hsiang-Tung Chang;Cerebral cortex;apical dendrite;dendritic potential;axonal initial segment;dendritic back-propagatingpotential;neuronal synaptic plasticity

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引用本文：

乔健天, 韩中胜, 祁金顺. 中枢神经元树突电活动和树突返传动作电位在突触可塑性调控中的作用-----悼念树突功能研究的先驱张香桐院士[J]. 生理学报 2008; 60 (2): 293-299.

Qiao Jiantian, Han Zhongsheng, Qi Jinshun. Electrophysiological characteristics of central neuronal dendrites and roles of dendritic back--propagating action potentials in modifications of synaptic plasticity. Acta Physiol Sin 2008; 60 (2): 293-299 (in Chinese with English abstract).