过刊浏览

激光照射胚泡对家兔和小鼠的抗早孕研究

丁爱华, 陈惠玲, 连少辉, 崔可心, 郑怀美

上海医科大学妇产科医院病理教研室. 上海；中国科学院上海生理研究所. 上海

摘要

本文在家兔、小鼠上探索了激光的抗旱孕效应,观察到血卟啉衍生物(HPD)和激光的光化效应能使早期胚泡完全坏死和吸收,无流血和晚期流产现象,通过PNQ_3荧光分光光度计测定HPD在胚胎组织中的荧光谱,证实HPD对胚胎组织有亲和力,其对滋养叶细胞比对宫壁组织的亲和力大4倍,借以解释激光光化效应抗早孕的可能机理。

关键词： 激光; 血卟啉; 抗旱孕; 荧光谱

Studies on terminaing early pregnancy of laser in rabbits and mice

Ding Aihua, Chen Huiling, Lian Shaohui, Cui Kexing, Zang Huaimei

Department of Pathology, Shanghai Medical University Hospital of Gynecology and Obstetrics；Shanghai Institute of Physiology, Academia Sinica；Shanghai Institute of Biochemistry, Academia Sinica

Abstract

Effect of laser on terminating early pregnancy in rabbits and mice showed that laser in combination with HPD could induce necrosis of blastocysts and complete
absorption. The anti-fertility efficiency of the combined treatment was more
effective than that of the He-Ne laser or the HPD treatment alone. The fluroescence spectrum of HPD determined by PNQ3 showed that its affinity to embryonic tissue was about 4 times greater than that to uterine tissue. These may underlie the mechanism of anti-early pregnancy of the laser.

Key words: Laser;Hematoporphrin;Terminating early pregnancy;Fluorescence spectrum

收稿日期：　　录用日期：

通讯作者：　　E-mail:

引用本文：

丁爱华, 陈惠玲, 连少辉, 崔可心, 郑怀美. 激光照射胚泡对家兔和小鼠的抗早孕研究[J]. 生理学报 1987; 39 (5): .

Ding Aihua, Chen Huiling, Lian Shaohui, Cui Kexing, Zang Huaimei. Studies on terminaing early pregnancy of laser in rabbits and mice. Acta Physiol Sin 1987; 39 (5): (in Chinese with English abstract).