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记录豚鼠耳蜗电位的外耳道慢性电极植入法

李兴启, 韩东一, 于黎明

解放军总医院耳鼻咽喉科

摘要

该文介绍用外耳道慢性电极植入法可以在较长时间内记录到清醒豚鼠的耳蜗电位(CAP和CM)。正常豚鼠的CAP[N_(1)]最大振幅平均达70—80μV。CAP[N_(1)]的潜伏期、阈值和最大振幅在4个月内均较稳定。因此用此法能远期观察清醒豚鼠耳蜗听功能的变化。

关键词： 耳蜗电位; 慢性电极; 豚鼠

A method of chronic electrode implantation for recording cochiear potentials from the external auditory chnal in guinea pigs

Li Xingqi, Han Dongyi, Yi Liming

Department of Otelaryngology, PLA General Hospital

Abstract

A method was described in this article for long term recording of the cochlear
potential (microphonics, compound action potential (CAP) of 8th nerve) from
external auditory canal in the awake guinea pig. The maximum amplitude of CAP [N_(1)] obtained in normal guinea pigs is 70-80 #mu#V. The results of the observation over a period of 4 months showed that the latency, threshold and maximum amplitude of CAP [N_(1)] are quite stable. The technique may be used for recording cochlear potential in the awake guinea pig over a long period.

Key words: Cochlear potential;Chronic electrode;Guinea pig

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引用本文：

李兴启, 韩东一, 于黎明. 记录豚鼠耳蜗电位的外耳道慢性电极植入法[J]. 生理学报 1987; 39 (4): .

Li Xingqi, Han Dongyi, Yi Liming. A method of chronic electrode implantation for recording cochiear potentials from the external auditory chnal in guinea pigs. Acta Physiol Sin 1987; 39 (4): (in Chinese with English abstract).