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健康早产儿睡眠时闪光视觉诱发电位的自回归分析

陈晓隆, 潘晓丽, 孟淑英

中国医科大学第二临床学院眼科.辽宁,沈阳 110004；中国医科大学第二临床学院神经内科脑电图室.辽宁,沈阳 110004；本溪市妇婴医院儿科.辽宁,本溪 117001

摘要

探讨闪光视觉诱发电位(FVEP)与健康早产儿视神经及脑发育间的关系。应用自回归分析法对36名健康早产儿(胎龄28周2天-42周)FVEP记录进行了分析,平均8.5个(7-11个)FVEP成分波被检出。依衰减频率分布的直方图将其分为4组。总功率(TP)、Ⅰ-Ⅳ组成分波功率(P)、Ⅱ-Ⅳ组衰减时间均随胎龄增加,有显著变化(P<0.01 or P<0.05)。提示神经系统对闪光刺激的生物电反应在早产儿脑及视神经发育评价上具有重要的临床意义。

关键词： 早产儿; 闪光视觉诱发电位; 自回归分析

Autoregressive analysis of flash evoked potentials in healthy preterm infants during sleep

Chen Xiaolong, Pan Xiaoli, Meng Shuying

Department of Ophthalmology,Second Hospital,China Medical University.Shenyang 110004,Liaoning；China

Abstract

To interpret the flash evoked potential (FVEP) as dynamic high-order responses to natural and experimental stimulation in healthy preterm infants, waveform analysis of FVEP in 36 healthy preterm infants (postconceptional age 28-42 weeks) were performed using an autoregressive analysis. Based on the histogram of damping frequency of different component impulse response waveforms, the waveforms were divided into 4 groups: group I (0-<2Hz), group II (2-<6.5Hz), group III (6.5-<12.0Hz) and group IV (12-25Hz). The total power, power of component impulse responses (group I-IV), and damping time (group II-IV) changed significantly with increasing postconceptional age (P<0.01 or P<0.05). Identification of an impulse response component with dominant frequency which undergoes a well-identified change with age is considered to be a useful tool for discriminating between normal and abnormal changes in the FVEP with age in healthy preterm infants.

Key words: Preterm infants;Flash visual evoked potential(FVEP);Autoregressive analysis

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引用本文：

陈晓隆, 潘晓丽, 孟淑英. 健康早产儿睡眠时闪光视觉诱发电位的自回归分析[J]. 生理学报 2002; 54 (5): .

Chen Xiaolong, Pan Xiaoli, Meng Shuying. Autoregressive analysis of flash evoked potentials in healthy preterm infants during sleep. Acta Physiol Sin 2002; 54 (5): (in Chinese with English abstract).