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电刺激大鼠脊神经皮支对远距离机械感受单位电活动的影响

贾军, 赵晏, 史文春, 王会生, 郭媛

西安交通大学医学院生理教研室.陕西,西安 710061

摘要

实验采用分离神经细束的方法,观察逆行电刺激大鼠脊神经背侧皮支后,在相距较远的神经细束上记录到的A#delta#和C类机械感受单位电活动的变化。刺激T9脊神经背侧皮支,在T12神经细束上记录到59.3%(16/27)的A#delta#和71.2%(37/52)的C类单位在刺激后90-120s放电显著增加。刺激T8脊神经背侧皮支,在T12神经细束上记录到47.8%(11/23)的A#delta#单位和36.6%(15/41)的C类单位在刺激后120-150s放电显著增加。大多数单位(18/23)的机械感受阈值在电刺激远距离脊神经背侧皮支后降低。结果表明,逆行电刺激外周感觉神经,可以使相距较远的A#delta#和C类机械感受单位致敏,其传入放电增加。

关键词： 机械感受单位; 分离神经细束; 传入放电; 电刺激; 感觉神经

Effects of electrical stimulation of the dorsal cutaneous branches of spinal nerves on the discharge activity of remote mechanoreceptive units in rats

Jia Jun, Zhao Yan, Shi Wenchun, Wang Huisheng, Guo Yuan

Department of Physiology,Medical School of Xi^an Jiaotong University.Xi^an 710062,Shaanxi

Abstract

The results suggest that antidromic electrical stimulation of the dorsal cutaneous branches of spinal nerves leads to sensitization of A#delta# and C mechanoreceptive units of the remote peripheral nerve endings, which results in an increase in afferent discharge of these units.

Key words: Mechanoreceptive units;Isolating nerve filaments;Afferent discharge;Electrical stimulation;Sensoy nerve

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引用本文：

贾军, 赵晏, 史文春, 王会生, 郭媛. 电刺激大鼠脊神经皮支对远距离机械感受单位电活动的影响[J]. 生理学报 2002; 54 (2): .

Jia Jun, Zhao Yan, Shi Wenchun, Wang Huisheng, Guo Yuan. Effects of electrical stimulation of the dorsal cutaneous branches of spinal nerves on the discharge activity of remote mechanoreceptive units in rats. Acta Physiol Sin 2002; 54 (2): (in Chinese with English abstract).