ISSN 0371-0874, CN 31-1352/Q

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区域性血管床对局部注射胍丁胺的不同反应

李清, 范振中, 王义和, 何瑞荣

河北医科大学基础医学研究所生理室.河北,石家庄 050017

摘要

在66只麻醉大鼠,分别采用后肢、肾脏和肠系膜动脉在体恒流灌注法,观察了向灌流环路中直接注射胍丁胺(agmatine,AGM)的血管效应,以所引起的灌流压增减反映血管的收缩和舒张。AGM对后肢、肾脏和肠系膜血管床的血管紧张性具有不同的作用。

关键词: 胍丁胺; 灌流压; 血管床; 咪唑啉受体; α2-肾上腺素能受体

Differential responses of regional vascular beds to local injection of agmatine in rats

Li Qing, Fan Zhenzhong, Wang Yihe, He Ruirong

Department of Physiology,Institute of Basic Medicine,Hebei Medical University.Shijiazhuang 050017,Hebei

Abstract

It is concluded that agmatine differentially affects the vascular tone in the femoral, renal, and mesenteric vascular beds.

Key words: Agmatine;Perfusion pressure;Vascular bed;Imidazoline receptor;#alpha#_(2) adrenoceptor receptor

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引用本文:

李清, 范振中, 王义和, 何瑞荣. 区域性血管床对局部注射胍丁胺的不同反应[J]. 生理学报 2001; 53 (6): .

Li Qing, Fan Zhenzhong, Wang Yihe, He Ruirong. Differential responses of regional vascular beds to local injection of agmatine in rats. Acta Physiol Sin 2001; 53 (6): (in Chinese with English abstract).