过刊浏览

肾缺血增强大鼠延髓腹外侧头端区神经元电活动和Fos蛋白表达

丁延峰, 张小雪, 石葛明, 何瑞荣

河北医科大学基础医学研究所生理研究室.河北,石家庄 050017；河北医科大学解剖教研室.河北,石家庄 050017

摘要

肾缺血增强延髓腹外侧头端区神经元的放电活动和Fos蛋白表达,而此作用可能与肾脏缺血所产生的腺苷激活肾内感受器有关。

关键词： 肾缺血; 延髓腹外侧头端区; 单位放电; Fos免疫组织化学; 腺苷; 8-苯茶碱

Renal ischemia enhances electrical activity and Fos protein expression of the rostral ventrolateral medullary neurons in rats

Ding Yanfeng, Zhang Xiaoxue, Shi Geming, He Ruirong

Departments of Physiology,Hebei Medical University.Shijiazhuang 050017,Hebei；China

Abstract

It is concluded that renal ischemia induces an increase in spontaneous electrical activity and Fos protein expression in PGL neurons of RVLM, and that adenosine released within ischemic kidney may be involved in such effects.

Key words: renal ischemia;Rostral ventrolateral medulla;Single- unit activity;Fos immunohistochemistry;Adenosine;8- phenyltheophylline

收稿日期：　　录用日期：

通讯作者：　　E-mail:

引用本文：

丁延峰, 张小雪, 石葛明, 何瑞荣. 肾缺血增强大鼠延髓腹外侧头端区神经元电活动和Fos蛋白表达[J]. 生理学报 2001; 53 (5): .

Ding Yanfeng, Zhang Xiaoxue, Shi Geming, He Ruirong. Renal ischemia enhances electrical activity and Fos protein expression of the rostral ventrolateral medullary neurons in rats. Acta Physiol Sin 2001; 53 (5): (in Chinese with English abstract).