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大鼠垂体细胞液泡内存在黄体生成激素(LH)

任惠民, 周寿康, 何志英, 顾敦瑜

复旦大学医学院神经病学研究所.上海 200040；上海市计划生育研究所.上海 200032

摘要

虽然哺乳动物不同组织的细胞液泡内含有许多相似的蛋白质成分,但LH是特异性地存在于垂体细胞液泡内。在这些LH分子中,至少有一部分是已经装配了糖基的完整LH分子。因此,垂体细胞的液泡有可能具有储存与释放LH的功能。

关键词： 垂体液泡; 黄体生成激素; 蛋白质; 糖蛋白

Identification of the existence of luteinizing hormone in pituitary vacuoles of rats

Ren Huimin, Zhou Shoukang, He Zhiying, Gu Dunyu

Institute of Neurology,Medical Center of Fudan University.Shanghai 200040；China

Abstract

It can be concluded that LH specifically exists in the pituitary vacuoles, although there are some similar protein components in various cellular vacuoles. The possibility was further demonstrated at the molecular level that the pituitary vacuoles may have the function of storing and releasing LH due to the pituitary vacuoles containing LH with assembled glycone.

Key words: Pituitary vacuole;LH;Protein;Glycoprotein

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引用本文：

任惠民, 周寿康, 何志英, 顾敦瑜. 大鼠垂体细胞液泡内存在黄体生成激素(LH)[J]. 生理学报 2001; 53 (5): .

Ren Huimin, Zhou Shoukang, He Zhiying, Gu Dunyu. Identification of the existence of luteinizing hormone in pituitary vacuoles of rats. Acta Physiol Sin 2001; 53 (5): (in Chinese with English abstract).