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L-精氨酸L-门冬氨酸盐对血小板功能的抑制

王银叶, 王景燕, 付逸龙, 王超, 彭师奇

北京大学药学院.北京 100083

摘要

DR可抑制血小板聚集和粘附功能,其作用机制不同于阿司匹林。这些作用部分是由于DR增加了血管内皮PGI_(2)的释放。结果为血小板功能的调节提供了新线索。

关键词： L-精氨酸; L-门冬氨酸盐; 血小板聚集; 血小板粘附; 血小板释放

Inhibition of platelet function by L-arginine·L-aspartate salt

Wang Yinye, Wang Jingyan, Fu Yilong, Wang Chao, Peng Shiqi

School of Pharmaceutical Sciences,Beijing University.Beijing 100083

Abstract

These data demonstrate the inhibitory effect of DR on platelet function, suggesting that its action target may be different from that of acetylsalicylic acid, and that the increase of PGI_(2) release may be responsible partly for this effect. It is suggested that DR may probably be used as a new agent for regulating platelet function.

Key words: L-Arginine;L-aspartate;Platelet aggregation;Adhesion;Release

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引用本文：

王银叶, 王景燕, 付逸龙, 王超, 彭师奇. L-精氨酸L-门冬氨酸盐对血小板功能的抑制[J]. 生理学报 2001; 53 (4): .

Wang Yinye, Wang Jingyan, Fu Yilong, Wang Chao, Peng Shiqi. Inhibition of platelet function by L-arginine·L-aspartate salt. Acta Physiol Sin 2001; 53 (4): (in Chinese with English abstract).