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乙酰胆碱对大鼠头端延髓腹外侧区前交感神经元放电的作用

王伟忠, 汪雪梅, 戎伟芳, 王继江, 袁文俊

第二军医大学基础医学部生理学教研室.上海 200433；安徽省卫生职工培训中心.安徽,合肥 230000

摘要

实验采用细胞外记录和微电泳等电生理方法,研究乙酰胆碱(ACh)对氨基甲酸乙酯麻醉的大鼠头端延髓腹外侧区(RVLM)前交感神经元放电频率的影响。结果提示,RVLM前交感神经元存在以M型受体介导的胆碱能纤维的紧张性兴奋投射。

Effect of acetylcholine on the discharge of presympathetic neurons of the rostral ventrolateral medulla of rats

Wang Weizhong, Wang Xuemei, Rong Weifang, Wang Jijiang, Yuan Wenjun

Department of Physiology,Second Military Medical University.Shanghai 200433；China

Abstract

Effect of acetylcholine (ACh) on presympathetic neurons of the rostral ventrolateral medulla (RVLM) was studied by extracellular recording technique and microiontophoresis in urethane-anaesthetized rats. The above finding suggests that presympathetic neurons of RVLM receive a tonic excitatory cholinergic input mediated by M receptors.

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引用本文：

王伟忠, 汪雪梅, 戎伟芳, 王继江, 袁文俊. 乙酰胆碱对大鼠头端延髓腹外侧区前交感神经元放电的作用[J]. 生理学报 2000; 52 (6): .

Wang Weizhong, Wang Xuemei, Rong Weifang, Wang Jijiang, Yuan Wenjun. Effect of acetylcholine on the discharge of presympathetic neurons of the rostral ventrolateral medulla of rats. Acta Physiol Sin 2000; 52 (6): (in Chinese with English abstract).