过刊浏览

自发性高血压大鼠心脏与红细胞L-Arg转运的改变

郑惠珍, 王晓红, 刘锡仪, 唐朝枢, 刘乃奎

广东医学院生理学教研室.广东,湛江 524023

摘要

研究自发性高血压大鼠(SHR)心脏L-精氨酸/一氧化氮(L-Arg/NO)系统的改变及其与红细胞L-Arg转运的关系。结果表明,SHR心室肌组织L-Arg/NO系统活动被抑制,其抑制程度与心肌肥厚程度呈负相关,红细胞L-Arg转运的改变与心脏L-Arg转运的改变一致。

The changes in the heart and erythrocyte L-arginine transport of spontaneously hypertensive rats

Zheng Huizhen, Wang Xiaohong, Liu Xiyi, Tang Chaoshu, Liu Naikui

Department of Physiology,Guangdong Medical College.Zhanjiang 524023,Guangdong

Abstract

Changes of L-arginine/nitric oxide pathway in heart and of L-arginine transport in erythrocytes and their relationship were investigated in spontaneously hypertensive rats (SHR). The results indicate that the activity of L-arginine/nitric oxide pathway inhibited in myocardial tissue of SHR. The correlation between the inhibitory degree of L-arginine/nitric oxide pathway and the degree of ventr icular hypertrophy is negative. The changes of L-arginine transport in erythrocytes coincide with those in myocardium.

收稿日期：　　录用日期：

通讯作者：　　E-mail:

引用本文：

郑惠珍, 王晓红, 刘锡仪, 唐朝枢, 刘乃奎. 自发性高血压大鼠心脏与红细胞L-Arg转运的改变[J]. 生理学报 2000; 52 (4): .

Zheng Huizhen, Wang Xiaohong, Liu Xiyi, Tang Chaoshu, Liu Naikui. The changes in the heart and erythrocyte L-arginine transport of spontaneously hypertensive rats. Acta Physiol Sin 2000; 52 (4): (in Chinese with English abstract).