过刊浏览

碱性成纤维细胞生长因子增加大鼠血管一氧化氮及内皮素的生成

姜志胜, 杨永宗, 赵文, 庞永政, 刘乃垣, 唐朝枢

衡阳医学院心血管病研究所.湖南,衡阳 421001；北京医科大学第一医院心血管研究所.北京 100034

摘要

研究碱性成纤维细胞生长因子(basic fibroblast growth factor,bFGF)对自发性高血压大鼠(SHR)和WKY大鼠血管一氧化氮(NO)及内皮素生成的影响。结果表明:bFGF对SHR和WKY大鼠主动脉NO及内皮素的产生具有调变作用。

Basic fibroblast growth factor increases nitric oxide and endothelin production in rat aorta

Jiang Zhisheng, Yang Yongzong, Zhao Wen, Pang Yongzheng, Liu Naikui, Tang Chaoshu

Research Institute of Cardiovascular Diseases,Hengyang Medical College.Hengyang 421001,Hunan；China

Abstract

The study was undertaken to investigate the effect of basic fibroblast growth factor (bFGF) on aortic production of nitric oxide (NO) and endothelin of aorta in spontaneously hypertensive rats (SHR) and WKY rats. It is concluded that bFGF may modulate the production of NO and endothelin in both SHR and WKY rats.

收稿日期：　　录用日期：

通讯作者：　　E-mail:

引用本文：

姜志胜, 杨永宗, 赵文, 庞永政, 刘乃垣, 唐朝枢. 碱性成纤维细胞生长因子增加大鼠血管一氧化氮及内皮素的生成[J]. 生理学报 2000; 52 (3): .

Jiang Zhisheng, Yang Yongzong, Zhao Wen, Pang Yongzheng, Liu Naikui, Tang Chaoshu. Basic fibroblast growth factor increases nitric oxide and endothelin production in rat aorta. Acta Physiol Sin 2000; 52 (3): (in Chinese with English abstract).