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肾动脉内注射缓激肽对麻醉家兔肾传入神经放电的双相激活

武宇明, 何瑞荣

河北医科大学基础医学研究所生理室.河北,石家庄 050017

摘要

肾内应用缓激肽所致ARNA初发相的激活,可归因于BK的直接作用及其所诱发NO的释放,延迟相的激活主要在于BK引起前列环素和NO释放的结果。

关键词： 缓激肽; 肾传入神经; 单位放电; 吲哚美辛; L-硝基精氨酸甲酯

Biphasic activation of renal afferent by intrarenal artery injection of bradykinin in anesthetized rabbits

Wu Yuming, He Ruirong

Department of Physiology,Hebei Medical University.Shijiazhuang 050017,Hebei

Abstract

It is concluded that intrarenal BK induces a significant increase in ARNA in two phases. The early phase may be due to the direct action of BK and partially due to the NO action, while the delayed phase may be attributed to the action of released prostaglandin and NO as a result of intrarenal BK.

Key words: Bradykinin;Renal afferent nerve;Unit-activity;Indomethecin;L-NAME

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引用本文：

武宇明, 何瑞荣. 肾动脉内注射缓激肽对麻醉家兔肾传入神经放电的双相激活[J]. 生理学报 1999; 51 (6): .

Wu Yuming, He Ruirong. Biphasic activation of renal afferent by intrarenal artery injection of bradykinin in anesthetized rabbits. Acta Physiol Sin 1999; 51 (6): (in Chinese with English abstract).