过刊浏览

下丘脑局部损毁对大鼠双侧催产素神经元爆发放电的影响

杨殿生, 王萍, 杨笑天, 王凯, 付纯芳, 王羽峰

佳木斯大学医学院生理学教研室.新疆,佳木斯 154002；日本福井医科大学临床医学检查部.福井 910-11,日本

摘要

观察了选择性脑切割损毁后的大鼠双侧视上核内催产素神经元在仔鼠吸吮刺激下射乳反射爆发放电。结果显示:在腹侧被盖以上横向切断单侧中脑中部,不能阻断双侧催产素神经元的同步化爆发放电;但是单侧下丘脑中间内侧部横切则可阻断这种同步化爆发放电。

关键词： 射乳反射; 爆发放电; 同步化中枢; 催产素神经元; 视上核; 下丘脑 大鼠

Effect of selective lesions in hypothalamus on bilateral synchronized bursts of rat oxytocin neurons

Yang Diansheng, Wang Ping, Yang Xiaotian, Wang Kai, Fu Chunfang, Wang Yufeng

Department of Physiology,Medical College of Jiamusi University.Jiamusi 154002,Xinjiang

Abstract

In order to clarify the location of the center for synchronized milk-ejection bursts of magnocellular oxytocin neurons in the hypothalamus, the bursts of these neurons were recorded extracellularly in lactating rats with selectively-cutting lesions of the middle brain or hypothalamus. Results showed that unilateral transection of the middle midbrain above the ventral tegmentum did not block the synchronized bursts on both sides; however, the synchronized bursts disappeared after unilateral transection through the middle of the medial hypothalamus.

Key words: Milk ejection reflex;Burst synchronization center;Oxytocin neuron;Supraoptic nucleus;Hypothalamus rat;

收稿日期：　　录用日期：

通讯作者：　　E-mail:

引用本文：

杨殿生, 王萍, 杨笑天, 王凯, 付纯芳, 王羽峰. 下丘脑局部损毁对大鼠双侧催产素神经元爆发放电的影响[J]. 生理学报 1999; 51 (4): .

Yang Diansheng, Wang Ping, Yang Xiaotian, Wang Kai, Fu Chunfang, Wang Yufeng. Effect of selective lesions in hypothalamus on bilateral synchronized bursts of rat oxytocin neurons. Acta Physiol Sin 1999; 51 (4): (in Chinese with English abstract).