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孕酮对人早孕子宫蜕膜细胞活性肾素分泌的调节

闫建设, 郭椋昊, 刘疆, 王红

中科院动物研究所计划生育生殖生物学国家重点实验室.北京 100080

摘要

孕酮可调节蜕膜细胞活性肾素的合成与分泌。人早孕子宫蜕膜组织中存在高水平的活性肾素,性类固醇激素可调节蜕膜细胞活性肾素的表达,子宫局部肾素-血管紧张素系统在妊娠过程中发挥了重要作用。

关键词： 孕酮; 肾素; 妊娠; 子宫蜕膜

Modulation of the secretion of active renin in human decidual cells by progesterone

Yan Jianshe, Guo Lianghao, Liu Jiang, Wang Hong

State Key Laboratory of Reproductive Biology,Institute of Zoology,Chinese Academy of Sciences.Beijing 100080

Abstract

The synthesis and secretion of active renin were regulated by progesterone in incubated decidual cells. These data indicate that a high level of active renin in decidual tissue at early pregnancy plays an important role in the uterine renin-angiotensin system during pregnancy.

Key words: Progesterone;Renin;Gestation;Human decidua

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引用本文：

闫建设, 郭椋昊, 刘疆, 王红. 孕酮对人早孕子宫蜕膜细胞活性肾素分泌的调节[J]. 生理学报 1999; 51 (2): .

Yan Jianshe, Guo Lianghao, Liu Jiang, Wang Hong. Modulation of the secretion of active renin in human decidual cells by progesterone. Acta Physiol Sin 1999; 51 (2): (in Chinese with English abstract).