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一氧化氮/内皮素在大鼠胃粘膜损伤中的作用及电针的调整效应

孙勇, 许冠荪, 刘维平, 许能贵

安徽中医学院针灸经络研究所生理研究室.安徽,合肥 230038

摘要

用酒精灌胃引起大鼠胃粘膜损伤模型,观察内皮衍生因子(NO/ET)的含量变化和电针对胃粘膜损伤调整作用。结果提示:NO有抗胃粘膜损伤作用,电针对胃粘膜保护作用的主要效应分子可能是NO。

关键词： 胃粘膜损伤; 一氧化氮; 内皮素; 电针

The role of NO/ET and the effect of electroacupuncture on injuried gastric mucosa in rats

Sun Yong, Xu Guansun, Liu Weiping, Xu Nenggui

Physiology Research Laboratory,The Institute of Acupuncture and Meridian,Anhui College of Traditional Chinese Medicine.Hefei 230038,Anhui

Abstract

The aim of the present work is to observe changes in endothelium-derived factors-nitric oxide (NO) and endothelin (ET), with special reference to the regu. Lative role of electroacupuncture (EA) in injured gastric mucosa of rat by ethanol. The resutls suggest that NO plays a critical part in protecting gastric mucosa against injury, which is also responsible for the protective effect of EA on injury of gastric mucosa.

Key words: Gastric mucosal injury;Nitric oxide (NO);Endothelin (ET);Electroacupuncture (EA)ic mucosa

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引用本文：

孙勇, 许冠荪, 刘维平, 许能贵. 一氧化氮/内皮素在大鼠胃粘膜损伤中的作用及电针的调整效应[J]. 生理学报 1999; 51 (2): .

Sun Yong, Xu Guansun, Liu Weiping, Xu Nenggui. The role of NO/ET and the effect of electroacupuncture on injuried gastric mucosa in rats. Acta Physiol Sin 1999; 51 (2): (in Chinese with English abstract).