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甘氨酸对鲫鱼视网膜ERG b-波和ON型双极细胞活动的调制

徐祥敏, 杨雄里

中科院上海生理研究所.上海 200031

摘要

甘氨酸能明显压抑ERG b-波和ON型双极细胞的反应,其作用能为士的宁所翻转;甘氨酸对用谷氨酸分离的ERG PIII成分(光感受器电位)无明显影响。

关键词： 甘氨酸; 视网膜电图(ERG); b-波; ON型双极细胞; 调制作用; 甘氨酸受体

Glycine modulates the ERG b-waves and on-type bipolar cells in carp retina

Xu Xiangmin, Yang Xiongli

Shanghai Institute of Physiology,Laboratory of Neurobiology,Chinese Academy of Sciences.Shanghai 200031

Abstract

It was revealed that application of 4 mmol/L glycine significantly suppressed by b-waves and the responses of ON-type bipolar cells and the effects were blocked by co-application of 20 #mu#mol/L strychnine. In addition, glycine had no apparent action on the P III component (photoreceptor potential) isolated by application of 3 mmol/L glutamate.

Key words: Glycine;ERG bwave;ON-type bipolar cell;Modulate;Glycine receptor;

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引用本文：

徐祥敏, 杨雄里. 甘氨酸对鲫鱼视网膜ERG b-波和ON型双极细胞活动的调制[J]. 生理学报 1999; 51 (2): .

Xu Xiangmin, Yang Xiongli. Glycine modulates the ERG b-waves and on-type bipolar cells in carp retina. Acta Physiol Sin 1999; 51 (2): (in Chinese with English abstract).