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胞内记录猫体感皮层内脏伤害性感受神经元的电生理特性

陈京红, 滕国玺

中国医科大学脑研究所神经生理研究室.辽宁,沈阳 110001

摘要

应用细胞内电位记录技术,观察了猫体感皮层内脏大神经皮层代表区的851个神经元对电刺激内脏大神经的诱发反应及电生理特性。结果说明皮层体感神经元具有内脏伤害性感受的作用,并从细胞及突触后电反应特点上探讨了内脏痛的感受机制。

关键词： 皮层体感区; 内脏; 伤害性感受; 细胞内记录; 标记; 痛

Intracellular electrophysiological characteristics of visceral nociceptive neurons in cortex SI area of cats

Chen Jinghong, Teng Guoxi

Laboratory of Neurophysiology,Brain Research Institute,China Medical University.Shenyang 110001,Liaoning

Abstract

In the present work we investigated electrophysiological properties of visceral nociceptive neurons in the primary somatosensory cortex (SI). Intracellular recordings of 851 neurons in the representing area of greater splanchnic nerve (GSN) in SI area were made in 22 cats. The neurons showed a variaty of modes in sponteneous discharges, which could be classified into visceral nociceptive neurons (VNNs) and non-visceral nociceptive neurons (NVNNs). VNNs (412) could be further divided into specific and non-specific subtypes, with three distinct response modes: excitatory, inhibitory, and mixed response.

Key words: Somatosensory cortex;Visceral;Nociceptive;Intracellular recording;Labeling;Pain

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引用本文：

陈京红, 滕国玺. 胞内记录猫体感皮层内脏伤害性感受神经元的电生理特性[J]. 生理学报 1999; 51 (1): 31-37.

Chen Jinghong, Teng Guoxi. Intracellular electrophysiological characteristics of visceral nociceptive neurons in cortex SI area of cats. Acta Physiol Sin 1999; 51 (1): 31-37 (in Chinese with English abstract).