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肥胖蛋白在小鼠组织的分布

高连如, 赵云涛, 朱智明, 石湘芸, 熊鉴然, 杨晔, 唐朝枢

解放军海军总医院.北京 100037；北京医科大学心肺内分泌研究室.北京 100083

摘要

应用放射免疫技术定量测定了小鼠脑、脂肪、肝、肌肉组织及血浆肥胖蛋白[OP-(57-92)]的含量。结果显示：小鼠脑组织OP含量最高,为13.14±0.8pg/mg;脂肪组织中OP含量为2.99±0.54pg/mg;肝脏及肌肉组织则未检测出OP。雌性小鼠脂肪组织中OP含量明显低于雄性(1.97±0.28vs4.02±0.92pg/mg)。小鼠的血浆中OP含量为2257.8±171.9pg/ml。

关键词： 肥胖蛋白剂; 小鼠

Distribution of obese protein in the mouse tissue

Gao Lianru, Zhao Yuntao, Zhu Zhiming, Shi Xiangyun, Xiong Jianran, Yang Ye, Tang Chaoshu

Navy General Hospital, People^s Liberation Army. Beijing 100037； China

Abstract

In the present study, the contents of obese protein of tissue from liver, brain, abdominal wall fat, skeletal muscle and the contents of plasma OP of mice were measured with radio immunoassay. The results showed that the contents of OP were much higher in the brain than that in the abdominal wall fat tissue (P<0.01). The liver and the skeletal muscle tissue did not show the presence of OP. The contents of OP of abdominal wall fat tissue were lower in the female than that in the male mice (P<0.05).

Key words: Obese protein mouse;Tissue

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引用本文：

高连如, 赵云涛, 朱智明, 石湘芸, 熊鉴然, 杨晔, 唐朝枢. 肥胖蛋白在小鼠组织的分布[J]. 生理学报 1997; 49 (2): .

Gao Lianru, Zhao Yuntao, Zhu Zhiming, Shi Xiangyun, Xiong Jianran, Yang Ye, Tang Chaoshu. Distribution of obese protein in the mouse tissue. Acta Physiol Sin 1997; 49 (2): (in Chinese with English abstract).