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兔孤束核腹外侧区微量注射谷氨酸钠及甘氨酸对膈神经放电的影响

刘诗翔, 魏书均, 周定邦, 范亚兰

成都军区昆明总医院神经科.云南,昆明 650032；昆明医学院生理教研室.云南,昆明 650031

摘要

实验在40只麻醉、制动、断双侧颈迷走神经和人工通气的家兔上进行。在孤束核腹外侧区微量注射谷氨酸钠,可使膈神经放电脉冲数明显增加,吸气时程延长,呼气时程缩短,呼吸频率变化不明显;微量注射甘氨酸,则膈神经放电脉冲数显著减少,甚至停止,吸气时程缩短,吸气时程不规则延长,呼吸频率降低。

关键词： 孤束核腹外侧区; 膈神经放电; 谷氨酸钠; 甘氨酸

Effects of microinjection of sodium glutamate and glycine into ventrolateral nucleus of tractus solitarius on the discharges of phrenic nerve in rabbits

Liu Shixiang, Wei Shujun, Zhou Dingbang, Fan Yalan

Department of Neurology, Kunming General Hospital. Kunming 650032, Yunnan； China

Abstract

The effects of microinjection of sodium glutamate and glycine into ventrolateral nucleus of tractus solitarius (VLNTS) on the discharges of phrenic nerve were observed on 40 anaesthetized, vagotomized, paralyzed and artificially ventilated rabbits. The results were as follows: Phrenic nerve discharges were increased. Inspiratory duration prolonged, expiratory duration shortened and respiratory frequency not changed by microinjection of sodium glutamate into VLNTS. While by microinjection of glycine, phrenic nerve discharges were decreased, even abolished, inspiratory duration shortened, expiratory duration irregularly prolonged and respiratory frequency decreased.

Key words: Ventrolateral nucleus of tractus solitarius;Phrenic nerve discharges;Sodium glutamate;Glycine glycine

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引用本文：

刘诗翔, 魏书均, 周定邦, 范亚兰. 兔孤束核腹外侧区微量注射谷氨酸钠及甘氨酸对膈神经放电的影响[J]. 生理学报 1997; 49 (2): .

Liu Shixiang, Wei Shujun, Zhou Dingbang, Fan Yalan. Effects of microinjection of sodium glutamate and glycine into ventrolateral nucleus of tractus solitarius on the discharges of phrenic nerve in rabbits. Acta Physiol Sin 1997; 49 (2): (in Chinese with English abstract).