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延缓go/no-go任务操作中猴尾核兴奋性氨基酸水平变化的微透析研究

尹萍波, 李葆明, 叶惟泠, 梅镇彤

中科院上海生理研究所.上海 200031

摘要

猴尾核透析液中的Glu和Asp水平较延缓go/no-go任务操作前基础水平分别降低(31.68±3.85)%(n=10)和(26.25±5.95)%(n=10),具有极显著的统计意义。同时,透析液中的Gln和Asn水平也显著降低(P<0.05)。相反,在没有延缓期的go/no-go任务和单纯的延缓go任务操作过程中,尾核透析液中Glu、Asp、Gln和Asn的水平均无显著性变化。

关键词: 尾核; 延缓go/no-go任务; 兴奋性氨基酸; 脑内微透析; 猕猴

A microdialysis study of excitatory amino acid levels of the monkey^s caudate nucleus during the delayed go/no-go task

Yin Pingbo, Li Baoming, Ye Weiling, Mei Zhentong

Shanghai Institute of Physiology, Chinese Academy of Sciences. Shanghai 200031

Abstract

Key words: Caudate nucleus;Delayed go/no-go task;Excitutory amino acid;Microdialysis;Monkey

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引用本文:

尹萍波, 李葆明, 叶惟泠, 梅镇彤. 延缓go/no-go任务操作中猴尾核兴奋性氨基酸水平变化的微透析研究[J]. 生理学报 1997; 49 (2): .

Yin Pingbo, Li Baoming, Ye Weiling, Mei Zhentong. A microdialysis study of excitatory amino acid levels of the monkey^s caudate nucleus during the delayed go/no-go task. Acta Physiol Sin 1997; 49 (2): (in Chinese with English abstract).