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脑桥呼吸调整中枢向延髓Botzinger复合体轴突投射的研究

宋刚, 于萍, 刘磊

山东医科大学生理学教研室. 山东, 济南 250012

摘要

Botzinger复合体内微量注入麦角辣根过氧化酶后, 在脑桥呼吸调整中枢结合臂外侧核及Kolliker-Fuse核观察到大量HRP标记神经元。结果表明发自脑桥呼吸调整中枢神经元的轴突可投射到Botzinger复合体, 该投射通路可能与呼吸调节有关。

关键词： 脑桥呼吸调整中枢; Botzinger复合体; 呼吸神经元; 逆行兴奋; 麦角辣根过氧化酶

Projections from pontine pneumotaxic center to medullary Botzinger complex in cats

Song Gang, Yu Ping, Liu Lei

Department of Physiology, Shandong Medical University. Jinan 250012, Shandong

Abstract

Experiments were done on 33 adult cats. After injection of WGA-HRP(5%, 30-60nl) into the Botzinger comples, labeled cells were observed in the lateral parabrachial nucleus and the Kolliker-Fuse nucleus. Injection into control sites failed to label the cells in the above two nuclei. Ninety-one respiratory related neurons recorded from the pneumotaxic center were tested by electrical stimulation of the Botzinger complex. Thirteen neurons(14.3%, inspiratory 11, phase-spanning 2)could be antidromically activated. Results of the present study showed that neurons in the pneumotaxic center sent axons to the Botzinger complex concerning respiratory control.

Key words: Pneumotoxic center;;;;

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引用本文：

宋刚, 于萍, 刘磊. 脑桥呼吸调整中枢向延髓Botzinger复合体轴突投射的研究[J]. 生理学报 1996; 48 (1): .

Song Gang, Yu Ping, Liu Lei. Projections from pontine pneumotaxic center to medullary Botzinger complex in cats. Acta Physiol Sin 1996; 48 (1): (in Chinese with English abstract).