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家兔离体心脏组织的不应期及房室结的滤波特性

张玲玲, 钮伟真, 刘北英, 焦晓慧, 刘萍

张家口医学院生理教研室. 河北, 张家口 075029；首都医科大学心血管研究室. 北京 100054

摘要

在短基础周期(200-300ms)家兔离体心脏组织房室结的相对不应期最长, 而在长基础周期(600、700ms)希浦系(His-Purkinje system)的相对不应期最长; 在多种基础周期下, 大多 数心脏(16/18)房室结有效不应期小于心房功能不应期; 快速起搏心房(周期140ms, n=7)时, 房室结维持1:1传导; 基础周期在200-700ms范围内, 房室结传导曲线始终是连续的。实 验提示: 在离体灌流条件下的成年家兔心脏, 其房室结没有滤波特性, 且不存具有生理意义的双径路。图3表1参15

关键词： 房室结; 滤波特性; 不应期; 房室结双径路; 家兔

Refractory periods of cardiac tissues and the filtering properties of the atrioventricular node in the isolated rabbit heart

Zhang Lingling, Niu Weizhen, Liu Beiying, Jiao Xiaohui, Liu Ping

Department of Physiology, Zhangjiakou Medical College. Zhangjiakou 075029, Hebei；China

Abstract

It is generally believed that the atrioventricular node (AVN) possesses filtering properties (FP) capable of preventing excess atrial impulses or earlier atrial premature beat from reaching the ventricle. In the present study, the refractory periods (RF) of cardiac tissues and the FP of the AVN were investigated in siolated rabbit hearts (n=18). It was found that: (1) relative RP of AVN was the longest at shorter basic cycle lengths (BCL) (200--300ms) while the relative RP of His--Purkinje system (HPS) was the longest at longer BCL (400, 700 ms). (2) The effective RP of AVN was shorter than the functional RP of the atrium in most cases (16/18) at any BCL. (3) During rapid atrial pacing at cycle length of 140 ms in 7 cases, AVN maintained 1:1 conduction. (4) the atrioventricular nodal conduction ncurve was smooth at BCL from 200 to 700 ms.

Key words: Atrioventricular node;Filtering properties;Refractory period;Dual A-V pathways;Rabbit

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引用本文：

张玲玲, 钮伟真, 刘北英, 焦晓慧, 刘萍. 家兔离体心脏组织的不应期及房室结的滤波特性[J]. 生理学报 1995; 47 (2): .

Zhang Lingling, Niu Weizhen, Liu Beiying, Jiao Xiaohui, Liu Ping. Refractory periods of cardiac tissues and the filtering properties of the atrioventricular node in the isolated rabbit heart. Acta Physiol Sin 1995; 47 (2): (in Chinese with English abstract).