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吸入不同浓度CO_(2)对肺通气功能影响的实验观察

陈芝村, 张丽君, 周殿敏, 张恒太

航天医学工程研究所

摘要

本实验在10名健康男性青年中观察了吸入0.5—7%CO_(2)对肺通气功能的影响。实验结果表明,呼吸频率、潮气量、肺通气量、肺泡CO_(2)分压以及肺通气对CO_(2)的反应性均与吸入气CO_(2)浓度成线性关系。被试者吸入CO_(2)后,CO_(2)排出量减少;但浓度不超过5%时,3—5min 内CO_(2)排出量即可基本恢复到正常水平。该文根据人体CO_(2)反应的这些特点提出了三个代偿区的意见。

关键词: 二氧化碳; 肺通气量; 肺泡CO_(2)分压; CO_(2)排出量; 代偿区

Experimental observation of influence of inhalating different concentrations of co_(2) on ventilatory function of the lungs

Chen Zhicun, Zhang Listun, Zhou Dianmin, Zhang Hengtai

Institute of Space Medico-Engineering

Abstract

Experiments were carried out on 10 healthy young subjects for observation of influence of inhalating 0.5-7% CO_(2) on the ventilatory function of the lungs. Respiratory rate, tidal volume, minute volume, alveolar Pco_(2) and the ventilatory sensitivity to CO_(2) were correlated with the concentration of CO_(2) in the inspired air. After CO_(2) inhalation, the output of CO_(2) expired decreased. It returned to the control level within 3-5 min, provided the concentration of CO_(2) in the inspired air was not more than 5%. According to the characteristics and patterns of human response to CO_(2) innaiauon, a suggestion of tnree compensatory areas was maae.

Key words: Carbon dioxide;Pulmonary ventilation;Alveolar P_(CO_(2));CO_(2) output;Compensatory area

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引用本文:

陈芝村, 张丽君, 周殿敏, 张恒太. 吸入不同浓度CO_(2)对肺通气功能影响的实验观察[J]. 生理学报 1985; 37 (1): .

Chen Zhicun, Zhang Listun, Zhou Dianmin, Zhang Hengtai. Experimental observation of influence of inhalating different concentrations of co_(2) on ventilatory function of the lungs. Acta Physiol Sin 1985; 37 (1): (in Chinese with English abstract).