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正常小鼠高频心电图时域值和功率谱的研究

艾洪滨, 崔希云, 唐琳, 朱卫平, 宁新宝, 杨秀侠

(山东师范大学生物系生理教研室，济南250014)； (南京大学电子科学与工程系，南京210093)

摘要

本文用南京新博公司生产的NHE-1000型心电高频信息检测分析仪研究了正常小鼠(昆明
种)高频心电图(HF-ECG)的时域值和QRS波群的功率谱。主要结果如下(以>(导为例，又士
SD):心率603士88次/min (n=74); P-R间期相对较长，为34.9士4. 7 ms (n=58)，占心动周
期的34.9士4.900，这与人类有很大的不同;QRS波宽9. 2士1. 2 ms，占心动周期的9.2士1.400(n=74)，这一结果与以前的文献报道相差较大。T波宽10.3士3.2 ms，占心动周期的10.3士3.200; Q-T间期19.4士3. 2 ms，占心动周期的19.5士3.600; QRS波群峰一峰值(VP-P)为1.456士0. 480 mV; T波高0.336士0. 115 mV; 73只动物B导联高频切迹总数只有3个，扭挫26个。B导联QRS波群的功率谱特点:0-80 Hz的相对能量为45.48士15. 32 0 o ; 80-200 Hz为43.97士9.9500;200-300 Hz为8.89士7. 38 0 o;300-1 000 Hz为1.66士2.74%.

关键词： 小鼠; HF-ECG ; 频响; 扫速; 功率谱

STUDIES ON THE TIME DOMAIN AND POWER SPECTRUM OF HIGH FREQUENCY ECG IN NORMAL MICE

AI Hong-Bin, CUI XI-YUN, TANG LIN , ZHU WEI-PING , NING XIN-BAO, YANG XIU-XIA

(Department of Biology , Shandong Normal University, Jinan 250014)； (Department of Electronic Sciences and Engineering Nanjing University, Nanjmg 210093)

Abstract

The features of time domain and power spectrum of high frequency electrocardiogram (HF-ECG) were studied in normal Kunming mice using a microprocessor ECG system. The results were as follows (X士SD):(1)P-R interval was 34. 9士4. 7 ms (n=58)，about one third of the cardiac cycle. (2) The duration and peak-to-peak amplitude of QRS complex were 9. 2士1. 2 ms and 1. 456士0. 480 mV (n=74) respectively. (3) The duration and amplitude of T wave were 10. 2士3. 2 ms and 0. 336士0. 115 mV, respectively (n=58). (4) Q-T interval was 19. 4士3. 2 ms (n=58)，about one fifth of the cardiac cycle. (5) The total number of notches and slurs of leads I of 73 mice were 3 and 26 respectively. (6) The relative power content of each frequency range was: 0一80 Hz:45. 48士15. 320o;80-200 Hz: 43. 97士9.9500;200-300 Hz: 8.89士7.830o;300-1000 Hz: 1. 66士2.740o; 80-1000 Hz:54. 52士15. 32%.

Key words: Mice; HF-ECG;time domain;power spectrum ;

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引用本文：

艾洪滨, 崔希云, 唐琳, 朱卫平, 宁新宝, 杨秀侠. 正常小鼠高频心电图时域值和功率谱的研究[J]. 生理学报 1996; 48 (5): .

AI Hong-Bin, CUI XI-YUN, TANG LIN , ZHU WEI-PING , NING XIN-BAO, YANG XIU-XIA. STUDIES ON THE TIME DOMAIN AND POWER SPECTRUM OF HIGH FREQUENCY ECG IN NORMAL MICE. Acta Physiol Sin 1996; 48 (5): (in Chinese with English abstract).