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延髓面神经后核内侧区呼吸相关神经元的放电形式

吴中海, 张枫桐, 徐小元

(第一军医大学生理学教研室，广州510515)

摘要

实验用家兔和SD大鼠，氨基甲酸乙酷麻醉(1 g/kg, iv or ip)。记录隔神经或隔肌放电作为呼吸的指标。在延髓面神经后核内侧区(mNRF)细胞外记录呼吸相关神经元((RRNs)放电，在家兔所记录到的249个RRNs中，吸气神经元118个(47.4%，可分4种亚型)，呼气神经元91个((36.500，包括4种亚型)，呼吸跨时相神经元40个(16. 100，包括E-1和1-E)。在大鼠所记录到的153个RRNs中，吸气神经元68个((44.5%)，呼气神经元55个((35.9%)，呼吸跨时相神经元30个(19.600)，在mNRF分布有较多的呼气一吸气跨时相神经元(E- I PS)，这类神经元放电总是先于隔神经吸气性放电，可能在基本呼吸节律发生中起重要作用。

关键词： 面神经后核内侧区; 呼吸神经元; 呼吸节律; 家兔; 大鼠

DISCHARGE PATTERNS OF RESPIRATORY RELATED NEURONES IN THE MEDIAL AREAS OF NUCLEUS RETROFACIALIS OF MEDULLA

WU ZHONG-HAI, ZHANG FANG-TONG, XU XlAO-YUAN

(Department of Physiology First Military Medical University, Gnangzlwu 510515)

Abstract

Experiments were performed on rabbits and SD rats，both anesthetized with urethane(1 .0 g/kg，iv or ip).Discharges of phrenic nerve and the diaphragmatic muscle electric activities were monitored. Discharge patterns of the respiration-related neurons (RRNs) in the medial area of nucleus retrofacialis (mNRF)were recorded and analyzed. Among the 249 RRNs recorded in the mNRF of the rabbits，118 were inspiratory (I，47. 4%)，91 expiratory (E，36. 5%)，and 40 phase-spanning (PS，16. 1%). Both 1 and E neurons could be further subdivided into 4 subtypes，the PS neurons into E-I and 1-E type. In the 153 RRNs recorded in rats, 68 were I (44. 5肠)，55 E(35.9%)，3 0 PS(19. 6%).It was found that a group of E-I PS neurons that fire preceding phrenic nerve respiratory activity are located in the mNRF，which was believed
to be important in the generation of the basic respiratory rhythm.

Key words: medial area of nucleus retrofacialis;Respiratory neurons;Respiratory rhythm;;

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引用本文：

吴中海, 张枫桐, 徐小元. 延髓面神经后核内侧区呼吸相关神经元的放电形式[J]. 生理学报 1997; 49 (4): .

WU ZHONG-HAI, ZHANG FANG-TONG, XU XlAO-YUAN. DISCHARGE PATTERNS OF RESPIRATORY RELATED NEURONES IN THE MEDIAL AREAS OF NUCLEUS RETROFACIALIS OF MEDULLA. Acta Physiol Sin 1997; 49 (4): (in Chinese with English abstract).