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核磁共振检测大鼠早期癫痫源性脑损伤的动态发展特征

臧颖, 韩丹, 杨运煌, 刘买利, 邹祖玉

武汉大学医学院生理学教研室.湖北,武汉 430071；中科院武汉物理与数学研究所波谱与原子分子物理国家重点实验室.湖北,武汉 430071；武汉大学医学院病理学教研室.湖北,武汉 430071

摘要

慢性强直电刺激大鼠CA1基树突区诱发大鼠癫痫点燃现象形成之前,LV区域T_(2)-WI信号增强具有背、腹方向以及跨半球动态扩布特征。预示了颞叶癫痫早期脑损伤形成中病理性神经网络的重建现象,其机制有待进一步探讨。

关键词： T_(2)加权核磁共振; 脑损伤; 癫痫

Development and progression in rat brain abnormalities related to early stage of epilepsy measured by magnetic resonance mage

Zang Ying, Han Dan, Yang Yunhuang, Liu Maili, Zou Zuyu

Departments of Physiology,Medical College,Wuhan University.Wuhan 430071,Hubei；China；Departments of Pathology,Medical College,Wuhan University.Wuhan 430071,Hubei

Abstract

The results suggest that the development of rat brain abnormalities from dorsal LV to ventral LV at early stage of epilepsy can be measured by magnetic resonance image, which implies reorganization of pathophysiologically functional networks before kindling effect appear.

Key words: Magnetic resonance image;Brain injuries;Epilepsy

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引用本文：

臧颖, 韩丹, 杨运煌, 刘买利, 邹祖玉. 核磁共振检测大鼠早期癫痫源性脑损伤的动态发展特征[J]. 生理学报 2002; 54 (3): .

Zang Ying, Han Dan, Yang Yunhuang, Liu Maili, Zou Zuyu. Development and progression in rat brain abnormalities related to early stage of epilepsy measured by magnetic resonance mage. Acta Physiol Sin 2002; 54 (3): (in Chinese with English abstract).