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植物性雌激素genistein对豚鼠乳头肌的电生理效应

马韬, 范振中, 何瑞荣

河北医科大学基础医学研究所生理室.河北,石家庄 050017

摘要

应用细胞内微电极技术,观察了genistein(GST)对豚鼠乳头肌的电生理效应。结果提示,GST可能通过非NO途径抑制Ca~(2+)内流,从而影响豚鼠乳头肌电生理效应,并与E_(2)有加强或协同效应。

关键词： 植物性雌激素; genistein; 乳头肌; 电生理; 17β-雌二醇

Electrophysiological effects of phytoestrogen genistein on guinea pig papillary muscles

Ma Tao, Fan Zhenzhong, He Ruirong

Department of Physiology,Institute of Basic Medicine,Hebei Medical University.Shijiazhuang 050017,Hebei

Abstract

The cardiac electrophysiological effects of genistein (GST) were examined in guinea pig papillary muscle using intracellular microelectrode technique.

Key words: Phytoestrogen;genistein;Papillary muscles;Electrophysiology;17#beta#-estradiol

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引用本文：

马韬, 范振中, 何瑞荣. 植物性雌激素genistein对豚鼠乳头肌的电生理效应[J]. 生理学报 2002; 54 (1): .

Ma Tao, Fan Zhenzhong, He Ruirong. Electrophysiological effects of phytoestrogen genistein on guinea pig papillary muscles. Acta Physiol Sin 2002; 54 (1): (in Chinese with English abstract).