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齿状回在慢性电刺激诱发大鼠颞叶癫痫中的可能作用

张先荣, 韩丹, 唐岳枫, 刘买利, 尹世金

武汉大学医学院生理学教研室.湖北,武汉 430071；中科院武汉物理与数学研究所波谱与原子分子物理国家重点实验室.湖北,武汉 430071

摘要

DG在内嗅皮质(EC)-HPC环路中可能起着某种“过滤器”的作用,限制来自于大脑皮层通过EC到达HPC的神经信息,一旦丧失该作用可以导致HPC的损害并发生颞叶癫痫。

关键词： 海马; 齿状回; 癫痫; T2加权核磁共振成像

Possible role of dentate gyrus in greneration of rat temporal lobe epilepsy induced by electrical stimulation

Zhang Xianrong, Han Dan, Tang Yuefeng, Liu Maili, Yin Shijin

Department of Physiology,Medical College,Wuhan University.Wuhan 430071,Hubei；China

Abstract

The results suggest that the DG acts as a filtering site in the entorhinal cortx-HPC neuronal circuitry and its dysfunction causes damage to the HPC and the generation of temporal lobe epilepsy.

Key words: Hipprrcampus;Dentate gyros;Epilepsy;T2-weighted magnetic resonance imaging (T_(2)-WI)

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引用本文：

张先荣, 韩丹, 唐岳枫, 刘买利, 尹世金. 齿状回在慢性电刺激诱发大鼠颞叶癫痫中的可能作用[J]. 生理学报 2001; 53 (3): .

Zhang Xianrong, Han Dan, Tang Yuefeng, Liu Maili, Yin Shijin. Possible role of dentate gyrus in greneration of rat temporal lobe epilepsy induced by electrical stimulation. Acta Physiol Sin 2001; 53 (3): (in Chinese with English abstract).