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不同频率电刺激膈神经导致膈肌肌浆网Ca~(2+)-ATPase和Ca~(2+)释放-摄取动力学改变

张睢扬, 刘刚, 王东林, 郭先健, 钱桂生

第三军医大学新桥医院全军呼吸内科研究所.重庆 400037

摘要

CES后不同频率CES导致膈肌SR Ca~(2+)-ATPase、Ca~(2+)摄取-释放动力学产生不同的适应性变化;对不同功能状态的膈肌应用不同频谱的慢性电刺激可能具有重要的临床意义。

关键词： 膈肌; Ca2+-ATPase; 动力学; 慢性电刺激

Changes in SR Ca~(2+)-ATPase activity, Ca~(2+) release and uptake kinetics of diaphragm muscle after different-frequency chronic electrical stimulation of diaphragmatic nerve

Zhang Suiyang, Liu Gang, Wang Donglin, Guo Xianjian, Qian Guisheng

Institute of Respiratory Medicine of Xinqiao Hospital,Third Military Medical University.Chongqing 400037

Abstract

It is thought that different frequency electrical stimulation induced different adaptative changes in SR Ca~(2+)-ATPase activity, and Ca~(2+) release and uptake kinetics of rabbit diaphragm muscle.

Key words: Diaphragm muscle;Ca~(2+)-ATPase;Kinetics;Chronic electrical stimulation

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引用本文：

张睢扬, 刘刚, 王东林, 郭先健, 钱桂生. 不同频率电刺激膈神经导致膈肌肌浆网Ca~(2+)-ATPase和Ca~(2+)释放-摄取动力学改变[J]. 生理学报 2001; 53 (3): .

Zhang Suiyang, Liu Gang, Wang Donglin, Guo Xianjian, Qian Guisheng. Changes in SR Ca~(2+)-ATPase activity, Ca~(2+) release and uptake kinetics of diaphragm muscle after different-frequency chronic electrical stimulation of diaphragmatic nerve. Acta Physiol Sin 2001; 53 (3): (in Chinese with English abstract).