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胍丁胺对离体大鼠主动脉张力的影响及其受体机制

李清, 何瑞荣

河北医科大学基础医学研究所生理室.河北,石家庄 050017

摘要

采用离体血管环灌流方法,观察了胍丁胺(Agm)对大鼠胸主动脉张力的影响,并探讨其受体机制。结果表明,Agm对大鼠主动脉血管的舒张作用是由#alpha#_(2)-AR和IR共同介导。

关键词： 胍丁胺; α_(2)-肾上腺素能受体; 咪唑啉受

Action of agmatine on tension of isolated aortic artery and its receptor mechanism in rats

Li Qing, He Ruirong

Department of Physiology,Institute of Basic Medicine,Hebei Medical University.Shijiazhuang 050017,Hebei

Abstract

The effect of agmatine (Agm) on vascular tension and the underlying receptor mechanism were investigated in the isolated aortic artery of rats.

Key words: Agmatine;#alpha#-(2) adrenergic receptor;Imidazoline receptor

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引用本文：

李清, 何瑞荣. 胍丁胺对离体大鼠主动脉张力的影响及其受体机制[J]. 生理学报 2001; 53 (2): .

Li Qing, He Ruirong. Action of agmatine on tension of isolated aortic artery and its receptor mechanism in rats. Acta Physiol Sin 2001; 53 (2): (in Chinese with English abstract).