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非NMDA受体参与双相呼气和吸气神经元电活动的调节

潘秉兴, 吴中海

第一军医大学生理学教研室.广东,广州 510515

摘要

使用非NMDA受体激动剂KA以后,双相呼气神经元的放电频率和峰频率都明显增大,吸气神经元中期放电的频率和峰频率也显著增大,而早期和晚期放电的频率无明显改变;用相应拮抗剂以后,上述效应明显被抑制。

关键词： 非NMDA受体; 双相呼气神经元; 吸气神经元; 放电频率; 峰频率; 突触输入

Non-NMDA receptors are involved in the modulation of discharge activity of biphasic expiratory neurons and inspiratory neurons

Pan Bingxing, Wu Zhonghai

Department of Physiology,The First Military Medical University.Guangzhou 510515,Guangdong

Abstract

Experiments were performed on in vitro brainstem slice preparations from neonatal rats that retain respiratory network activity.

Key words: noir NMDA receptor;Biphasic expiratoiy neuron;Inspiratoiy neuron;Discharge frequency;Peak frequency;Synaptic input

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引用本文：

潘秉兴, 吴中海. 非NMDA受体参与双相呼气和吸气神经元电活动的调节[J]. 生理学报 2001; 53 (2): .

Pan Bingxing, Wu Zhonghai. Non-NMDA receptors are involved in the modulation of discharge activity of biphasic expiratory neurons and inspiratory neurons. Acta Physiol Sin 2001; 53 (2): (in Chinese with English abstract).