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肾神经在肾缺血预处理对麻醉家兔心脏保护中的作用

丁延峰, 张蔓蔓, 何瑞荣

河北医科大学基础医学研究所生理研究室.河北,石家庄 050017

摘要

在氨基甲酸乙酯麻醉家兔上,观察肾脏缺血预处理(RIP)对缺血-再灌注心肌的影响,旨在证实RIP对心肌有无保护效应,并明确肾神经在其中的作用。结果表明,肾短暂缺血-再灌注所诱发的肾神经传入活动在RIP心肌保护效应中起重要作用。

关键词： 缺血-再灌注; 远程缺血预处理; 肾缺血; 肾神经传入放电活动; 心脏; 8-苯茶碱

Role of renal nerve in cardioprotection provided by renal ischemic preconditioning in anesthetized rabbits

Ding Yanfeng, Zhang Manman, He Ruirong

Department of Physiology,Institute of Basic Medicine,Hebei Medical University.Shijiazhuang 050017,Hebei

Abstract

The effects of renal ischemic preconditioning (RIP) on ischemia-reperfused myocardium were examined in the urethane-anesthetized rabbit to determine whether RIP may provide cardioprotection and to observe the role of the renal nerve in such condition.

Key words: Ischemia-reperfusion;remote ischemic preconditioning;renal ischemia;renal afferent activity;Heart;8-phenyltheophylline

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引用本文：

丁延峰, 张蔓蔓, 何瑞荣. 肾神经在肾缺血预处理对麻醉家兔心脏保护中的作用[J]. 生理学报 2001; 53 (1): .

Ding Yanfeng, Zhang Manman, He Ruirong. Role of renal nerve in cardioprotection provided by renal ischemic preconditioning in anesthetized rabbits. Acta Physiol Sin 2001; 53 (1): (in Chinese with English abstract).