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Ca~(2+)在链霉素对大鼠颈动脉窦压力感受器反射影响中的作用

秦晓梅, 何瑞荣

河北医科大学基础医学研究所生理室.河北,石家庄 050017

摘要

在23只隔离灌流颈动脉窦区的麻醉大鼠上,观察了链霉素(streptomycin,SM)对动脉压力感受器反射影响的离子机制。结果表明,SM可能是通过抑制颈动脉窦压力感受器中机械敏感性通道的Ca~(2+)内流而发挥作用。

Role of calcium in the mechanism underlying the inhibitory effect of streptomycin on carotid sinus baroreflex in rats

Qin Xiaomei, He Ruirong

Department of Physiology,Institute of Basic Medicine,Hebei Medical University.Shijiazhuang 050017,Hebei

Abstract

The effect of streptomycin (SM) on carotid baroeflex was examined in 23 anesthetized rats with isolated carotid sinus perfusion. Results suggest that the inhibitory action of SM on carotid baroreflex may be mediated by suppressing Ca~(2+) influx.

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引用本文：

秦晓梅, 何瑞荣. Ca~(2+)在链霉素对大鼠颈动脉窦压力感受器反射影响中的作用[J]. 生理学报 2000; 52 (6): .

Qin Xiaomei, He Ruirong. Role of calcium in the mechanism underlying the inhibitory effect of streptomycin on carotid sinus baroreflex in rats. Acta Physiol Sin 2000; 52 (6): (in Chinese with English abstract).