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枸橼酸转运蛋白mRNA在代谢性酸中毒大鼠肾组织的表达

吴镝, 陈香美, 叶一舟, 程庆砾, 王建忠

北京解放军总医院肾科,解放军肾脏病中心暨重点实验室.北京 100853

摘要

在代谢性酸中毒时,大鼠肾小管上皮细胞两侧钠离子依赖的枸橼酸膜转运蛋白mRNA表达量增加,肾脏对枸橼酸的重吸收能力可能增强。

关键词： 枸橼酸转运蛋白; 酸中毒; 肾脏

Expression of citrate transporter mRNA in the kidneys of rats with metabolic acidosis

Wu Di, Chen Xiangmei, Ye Yizhou, Cheng Qingli, Wang Jianzhong

Division of Nephrology,General Hospital of Chinese PLA.Beijing 100853

Abstract

It is concluded that metabolic acidosis can induce increase of Na~(+)/citrate cotransporter mRNA, which may be responsible for hypocitraturia.

Key words: Citrate transporter;Acidosis;Kidney

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引用本文：

吴镝, 陈香美, 叶一舟, 程庆砾, 王建忠. 枸橼酸转运蛋白mRNA在代谢性酸中毒大鼠肾组织的表达[J]. 生理学报 2000; 52 (1): .

Wu Di, Chen Xiangmei, Ye Yizhou, Cheng Qingli, Wang Jianzhong. Expression of citrate transporter mRNA in the kidneys of rats with metabolic acidosis. Acta Physiol Sin 2000; 52 (1): (in Chinese with English abstract).