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利用核磁共振同时观察大鼠心室内压参数与能量代谢

程增江, 杜泽涵, 李红昕, 董华进, 冯锐, 李光玉

军事医学科学院国家生物医学分析中心.北京 100850；山东省立医院心外科.山东,济南 250021；军事医学科学院毒物药物研究所.北京 100850

摘要

关键词： 核磁共振; 离体心脏; 能量代谢

Simultaneous observation of parameter of intraventricular pressure and energy metabolism in rat hearts using nuclear magnetic resonance

Cheng Zengjiang, Du Zehan, Li Hongxin, Dong Huajin, Feng Rui, Li Guangyu

National Center for Biomedical Analysis,Academy of Military Medical Science.Beijing 100850；China；Institute of Pharmacolgy and Toxicology,AMMS.Beijing 100850

Abstract

A technique for simultaneous observation of parameters of intraventricular pressure and energy metabolic status in isovolumic rat hearts was described. The parameters of intraventricular pressure were collected and processed using a computerized monitoring system for heart function, and myocardial energy metabolism was investigated by collecting the ~(31)P NMR spectra. The preparation was stable metabolically and functionally for 2 h under the NMR experimental conditions.

Key words: NMR;Isolated heart;Energy metabolism

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引用本文：

程增江, 杜泽涵, 李红昕, 董华进, 冯锐, 李光玉. 利用核磁共振同时观察大鼠心室内压参数与能量代谢[J]. 生理学报 1999; 51 (6): .

Cheng Zengjiang, Du Zehan, Li Hongxin, Dong Huajin, Feng Rui, Li Guangyu. Simultaneous observation of parameter of intraventricular pressure and energy metabolism in rat hearts using nuclear magnetic resonance. Acta Physiol Sin 1999; 51 (6): (in Chinese with English abstract).