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颈动脉内注射腺苷对去缓冲神经大鼠最后区神经元放电的影响

陈爽, 何瑞荣

河北医科大学基础医学研究所生理室.河北,石家庄 050017

摘要

腺苷对AP区神经元自发放电有抑制作用,而此作用与A_(1)受体介导的ATP敏感性钾通道开放有关。

关键词： 腺苷; 最后区; 自发放电单位; 8-苯茶碱; 8-环戊1 3-二丙基黄嘌呤; 格列苯脲

Effect of intracarotid administration of adenosine on the activity of area postrema neurons in barodenervated rats

Chen Shuang, He Ruirong

Department of Physiology,Hebei Medical University.Shijiazhuang 050017,Hebei

Abstract

The results indicate that Ado can inhibit spontaneous electrical activity of AP neurons, which is mediated by adenosine A_(1)-receptor with the involvement of ATP-sensitive potassium channels.

Key words: Adenosine;Area postrema;Spontaneous single unit discharge;8-phenyltheophylline;8-cyclopentyl-1;3-dipropylxanthine

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引用本文：

陈爽, 何瑞荣. 颈动脉内注射腺苷对去缓冲神经大鼠最后区神经元放电的影响[J]. 生理学报 1999; 51 (6): .

Chen Shuang, He Ruirong. Effect of intracarotid administration of adenosine on the activity of area postrema neurons in barodenervated rats. Acta Physiol Sin 1999; 51 (6): (in Chinese with English abstract).