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膳食锌对小鼠脑组织微管相关蛋白2表达的影响

王福di, 赵法ji, 景乃禾

第二军医大学海军卫生学教研室.上海 200433；中科院上海生物化学研究所.上海 200031

摘要

缺锌可明显抑制脑组织中MAP2表达,补充锌即可显著促进MAP2表达;MAP2表达量降低可能是锌缺乏引发微管聚合作用下降的重要机制之一。

关键词： 锌; 脑发育; 脑功能; 微管相关蛋白2

Effect of dietary zinc on microtubule-associated protein 2 expression in the brain of mice

Wang Fudi, Zhao Faji, Jing Naihe

Department of Naval Medicine,Second Military Medical University.Shanghai 200433；China

Abstract

Zinc deficiency may inhibit the MAP2 expression, while zinc supplement exerts much improvement. The lowered level of MAP2 expression is one of important mechanisms underlying impairments of microtubule polymerization, as a result of zinc deficiency.

Key words: Zinc;Brain development;Brain function;Microtubule-associated protein 2

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引用本文：

王福di, 赵法ji, 景乃禾. 膳食锌对小鼠脑组织微管相关蛋白2表达的影响[J]. 生理学报 1999; 51 (5): .

Wang Fudi, Zhao Faji, Jing Naihe. Effect of dietary zinc on microtubule-associated protein 2 expression in the brain of mice. Acta Physiol Sin 1999; 51 (5): (in Chinese with English abstract).