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重组人肝细胞生成素的生物学性能

张咏, 杨晓明, 王阁, 贺福初

北京放射医学研究所.北京 100850；第三军医大学大坪医院消化科

摘要

首次利用基因工程产品rhHPO,以多种细胞系为靶细胞,对rhHPO的生物学活性进行了较全面的研究。

Biological activity of recombinant human hepatopoietin

Zhang Yong, Yang Xiaoming, Wang Ge, He Fuchu

Institute of Radiation Medicine.Beijing 100850

Abstract

rhHPO is an important stimulating factor of regeneration, which may be developed as a potential drug for the treatment of severe hepatic diseases. The authors found an inhibitory effect of rhHPO on the DNA synthesis of lung cancer cell lines GLC-82 in vitro, which might provide a valuable indicator for the study of its specificity and mechanisms.

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引用本文：

张咏, 杨晓明, 王阁, 贺福初. 重组人肝细胞生成素的生物学性能[J]. 生理学报 1999; 51 (3): .

Zhang Yong, Yang Xiaoming, Wang Ge, He Fuchu. Biological activity of recombinant human hepatopoietin. Acta Physiol Sin 1999; 51 (3): (in Chinese with English abstract).