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5-羟色胺和胃动素在狗小肠移行性复合运动调控中的作用

摘要

应用慢性植入小肠腔外应力传感器记录清醒狗小肠移行性复合运动(MMC)。在颈外静脉和支配10-15cm肠段的空肠动脉内分别放置一硅胶管以备灌流药物和取血样品用。观察了静脉和动脉注射药物对小肠MMC的影响及MMC不同时相血浆5-羟色胺(5-HT)和胃动素的浓度变化。

关键词： 移行性复合运动; 5-羟色胺; 胃动素

Regulatory role of 5-hydroxytryptamine and motilin in migrating motor complex of small bowel in dogs

Abstract

Migrating motor complex (MMC) was recorded by chronically implanted strain gauge transducers on the serosa of small bowel in conscious dogs. Two silastic catheters for injecting drugs and taking blood samples were put respectively in a vena jugularis extema and in a jejunal artery which perfused a 10-15 cm intestinal segment. The present study was undertaken to observe the effect of drugs administered intravenously and intra-arterially on MMC and alterations of plasma 5-hydroxytryptamine (5-HT) and motilin in different phases of MMC.

Key words: Migrating motor complex;5-hydroxytryptamine;Motilin

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引用本文：

. 5-羟色胺和胃动素在狗小肠移行性复合运动调控中的作用[J]. 生理学报 1998; 50 (4): .

. Regulatory role of 5-hydroxytryptamine and motilin in migrating motor complex of small bowel in dogs. Acta Physiol Sin 1998; 50 (4): (in Chinese with English abstract).