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大鼠心率变异性频谱中高频成分的中枢机理分析

摘要

探讨心率变异性(HRV)频谱中高频成分的中枢机理。对正常SD大鼠给予不同频率的人工通气并电刺激延髓疑核,观察HRV频谱的改变,记录与呼吸节律同步的延髓头端腹外侧区(rVLM)及其周围区神经元细胞外单位放电,对HRV和放电变异性进行相干函数分析。

关键词： 大鼠; 心率变异性; 神经元放电变异性; 疑核; 谱分析; 延髓头端腹外侧区

The central mechanism of the high frequency component in heart rate variability in rat

Abstract

Experiments were performed on 15 Sprague-Dawley rats to detect the effect of artificial ventilation of different frequencies on the high frequency component of heart rate variability (HBV) by autoregressive modeling with Burg algorithm. With continuous or intermittent electrical stimulation, different patterns of regulating activity of nucleus ambiguus in medulla on HRV were observed. Fast Fourier transform was used to analyze the coherence between neuronal discharge with respiratory rhythm in rostral ventrolateral medulla (rVLM) and HRV.

Key words: Rat;Heart rate variability;Neurongl discharge variability;Nucleus ambiguus; Spectral analysis;Rostral ventrolateral medulla

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引用本文：

. 大鼠心率变异性频谱中高频成分的中枢机理分析[J]. 生理学报 1998; 50 (4): .

. The central mechanism of the high frequency component in heart rate variability in rat. Acta Physiol Sin 1998; 50 (4): (in Chinese with English abstract).