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腺苷对颈动脉窦压力感受器反射的易化作用

摘要

在27只隔离灌流颈动态窦区的麻醉大鼠,观察了腺苷(Ado)对颈动态窦压力感受器反射的影响。结果表明,Ado对大鼠颈动脉窦压力感受器活动有易化作用,这一作用似与腺苷A_(1)受体介导的K_(ATP)通道开放有关。

关键词： 腺苷; 颈动脉窦压力感受器反射; 平均动脉压

Anenosine facilitates carotid baroreflex in rats

Abstract

The effects of adenosine (Ado) on the carotid baroreflex were studied in 27 anesthetized rats wit isolated carotid sinus perfusion. The results strongly suggest that the carotid baroreflex could be facilitated by Ado. It is proposed that the facilitatory action of Ado on carotid baroreflex may be resulted from the opening of K_(ATP) channels mediated by Ado A_(1)-receptors.

Key words: Adenosine;Carotid baroreflex;Mean arterial pressure

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引用本文：

. 腺苷对颈动脉窦压力感受器反射的易化作用[J]. 生理学报 1998; 50 (3): .

. Anenosine facilitates carotid baroreflex in rats. Acta Physiol Sin 1998; 50 (3): (in Chinese with English abstract).