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GABA参与兔杏仁体抑制内膝体神经元电活动

摘要

采用多管微电极胞外记录技术观察了短纯音引起兔内膝体(MGB)神经元的声反应及刺激杏仁体对声反应的影响,并在此基础上观察电泳GABA及其拮抗剂Bicuculline的效应。实验结果表明:介导杏仁体抑制MGB神经元声反应的最终递质是GABA。

关键词： 杏仁体; 抑制; 内膝体; CABA

GABA mediated inhibitory effect of amygdala on the activity of medial geniculate body neurons

Abstract

On 10 New Zealand white rabbits immobilized with Flaxedil, the inhibitory effect of amygdaloid stimulation on the responses of medial geniculate body (MGB) neurons to tone bursts and the involved neurotransmitter mechanism were investigated with microiontophoresis technique. It seemed unlikely that glycine was involved in the effect, since strychnine, a glycine antagonist, could not affect the descending inhibition from ACBRS area.

Key words: Amygdala;Inhibitory;MGB;GABA

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引用本文：

. GABA参与兔杏仁体抑制内膝体神经元电活动[J]. 生理学报 1998; 50 (3): .

. GABA mediated inhibitory effect of amygdala on the activity of medial geniculate body neurons. Acta Physiol Sin 1998; 50 (3): (in Chinese with English abstract).