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热休克反应对培养的大鼠脑星形胶质细胞的保护作用及对其IL-6分泌的影响

摘要

热休克反应能增强星形胶质细胞对H_(2)O_(2)耐受力。热休克反应后6h,星形胶质细胞IL-6释放明显增多。结果提示,IL-6分泌的增加可能是热休克反应的细胞保护作用机制之一。

关键词： 热休克反应; 星形胶质细胞; 白细胞介素-6

Heat shock response induces resistance to hydrogen peroxide and increases synthesis of interleukin-6 in rat astrocyte in vitro

Abstract

Cell viability and cell membrane disruption of rat astrocyte after heat shock response (HSR) were assessed by the analysis of MTT reduction and lactate dehydrogenase (LDH) release.

Key words: Heat shock response;Astrocyte;Interleukin-6

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引用本文：

. 热休克反应对培养的大鼠脑星形胶质细胞的保护作用及对其IL-6分泌的影响[J]. 生理学报 1998; 50 (3): .

. Heat shock response induces resistance to hydrogen peroxide and increases synthesis of interleukin-6 in rat astrocyte in vitro. Acta Physiol Sin 1998; 50 (3): (in Chinese with English abstract).