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钙超载和血小板激活因子对肺组织释放降钙素基因相关肽的影响

摘要

肠缺血/再灌注(L/R)损伤后血浆中降钙素基因相关肽(CGRP)浓度显著升高而肺灌洗液中CGRP的变化不明显;体外肺组织释放CGRP可能同胞内钙离子增加和磷脂酶A_(2)激活及PAF合成增加相关;SR27417A可以阻断PAF的促CGRP释放作用,但在体内外均有显著的促CGRP释放的作用。

关键词： 肠缺血／再灌注损伤; 磷脂酶A_(2); 降钙素基因相关肽; 血小板激活因子

Effect of calcium overload and platelet activating factor on calcitonin gene related peptide release from lung tissue

Abstract

Key words: Intestinal ischemia/reperfusion;Calcitonin gene related peptide;Phospholipase A_(2);Platelete activating factor

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引用本文：

. 钙超载和血小板激活因子对肺组织释放降钙素基因相关肽的影响[J]. 生理学报 1998; 50 (1): .

. Effect of calcium overload and platelet activating factor on calcitonin gene related peptide release from lung tissue. Acta Physiol Sin 1998; 50 (1): (in Chinese with English abstract).